KIAA1841

Across TCGA patient cohorts, KIAA1841 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1841-associated genes across cancer lineages are EGFR_pY1173, ERK2, and MEK1_p_S217_S221. Each is linked with KIAA1841 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1841-to-partner and partner-to-KIAA1841 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1173 grouped by KIAA1841-low versus KIAA1841-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1841→partner) and Y-score (partner→KIAA1841) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1173 →	+0.079	+3.169	.011	.018	3	2
UCEC	ERK2 →	+0.199	+2.000	.008	.010	3	2
UCEC	MEK1_p_S217_S221 →	-0.258	-2.000	.015	.030	3	2
UCEC	c-Met_pY1235 →	+0.058	+2.009	.046	.017	3	2
UCEC	EGFR_pY1068 →	-0.269	-2.502	.006	.002	3	1
UCEC	A-Raf_pS299 →	-0.105	-3.321	.025	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

EGFR_pY1173 by KIAA1841 expression — UCEC

Explore this box plot interactively →