KIAA1841

Across TCGA pan-cancer cohorts, KIAA1841 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated KIAA1841 data layer compared with 4 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher KIAA1841 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KIAA1841 expression acts as an unfavorable survival marker, although some lineages such as READ and COAD show a favorable association.

MESO, ACC, and LIHC are the cancer types where KIAA1841 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.379	0.705	<.001	132	view →
ACC	DFS	Median	All	0.406	0.748	<.001	112	view →
LIHC	DFS	Median	All	0.436	0.643	<.001	107	view →
KICH	OS	Median	II,III,IV	0.627	1.000	<.001	93	view →
KIRC	DFS	Quartile	III,IV	0.216	0.621	<.001	83	view →
READ	OS	Median	II,III,IV	0.834	0.404	<.001	69	view →
COAD	OS	Median	IV	0.785	0.352	<.001	68	view →
LGG	OS	Median	All	0.736	0.876	<.001	42	view →
SARC	OS	Median	All	0.447	0.736	<.001	31	view →
BLCA	DFS	Tertile	All	0.392	0.626	.007	26	view →
THYM	DFS	Median	All	0.967	0.617	.003	22	view →
UVM	DFS	Quartile	III,IV	0.231	0.735	.016	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

KIAA1841–MESO (OS)

Open the MESO breakdown →