KIAA1755

Across TCGA cell cohorts, KIAA1755 mutation is significantly associated with the RNA expression of many other genes, with 887 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1755-associated genes across cancer lineages are C12orf60, FAM86B1, and OR52A1. Each is linked with KIAA1755 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA1755-to-partner and partner-to-KIAA1755 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C12orf60 grouped by KIAA1755-low versus KIAA1755-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1755→partner) and Y-score (partner→KIAA1755) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C12orf60 →	+0.577	+3.523	<.001	<.001	3	3
LARGE_INTESTINE	FAM86B1 →	+1.046	+2.628	<.001	.002	3	3
SKIN	OR52A1 →	+0.031	+3.418	.001	<.001	3	2
STOMACH	OR5H2 →	+0.207	+4.285	<.001	.007	3	2
CNS	KERA →	+0.096	+4.096	.001	.001	3	2
LARGE_INTESTINE	L3MBTL2 →	+0.573	+2.628	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 887 associations by consensus.

C12orf60 by KIAA1755 expression — LARGE_INTESTINE

Explore this box plot interactively →