KIAA1671

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1671 mutation is significantly associated with the total protein of many other genes, with 72 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KIAA1671-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and GAPDH. Each is linked with KIAA1671 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA1671-to-partner and partner-to-KIAA1671 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1671→partner) and Y-score (partner→KIAA1671) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADEGFR_pY1068 →-0.366-3.309.004.00932
UCECeIF4E →+0.223+1.906<.001<.00132
COADGAPDH →+0.614+2.123.001.01032
UCECMSH2 →-0.285-3.061<.001<.00132
UCECMSH6 →-0.333-1.906<.001.01432
UCECS6_pS240_S244 →+0.284+1.598.016.01932
Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

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