KIAA1614-AS1

Across TCGA pan-cancer cohorts, KIAA1614-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated KIAA1614-AS1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher KIAA1614-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIAA1614-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LAML show a favorable association.

LIHC, HNSC, and KICH are the cancer types where KIAA1614-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Quartile	All	0.432	0.685	<.001	56	view →
HNSC	DFS	Median	IV	0.649	0.449	<.001	45	view →
KICH	DFS	Quartile	II,III,IV	0.282	0.940	.001	42	view →
LAML	DFS	Tertile	All	0.650	0.273	.002	34	view →
STAD	OS	Quartile	IV	0.132	0.629	.003	25	view →
LGG	OS	Median	All	0.858	0.929	<.001	23	view →
MESO	DFS	Median	All	0.214	0.629	.002	21	view →
KIRC	OS	Median	All	0.567	0.712	.003	17	view →
PAAD	DFS	Tertile	II,III,IV	0.596	0.305	.005	14	view →
READ	OS	Median	IV	0.995	0.486	<.001	14	view →
ESCA	DFS	Tertile	IV	0.216	0.562	.047	12	view →
KIRP	DFS	Quartile	IV	0.038	0.528	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

KIAA1614-AS1–LIHC (DFS)

Open the LIHC breakdown →