KIAA1614-AS1

Across TCGA pan-cancer cohorts, KIAA1614-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KIAA1614-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KIAA1614-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types KIAA1614-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where KIAA1614-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA1614-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	−0.301	<.001	10	view →
THCA	All	II,III,IV	−0.189	<.001	9	view →
LIHC	Male	All	+0.235	<.001	8	view →
HNSC	All	II,III,IV	+0.108	<.001	7	view →
LUAD	All	All	+0.136	.001	5	view →
LUSC	Male	All	+0.154	<.001	3	view →
COAD	All	All	+0.073	.014	3	view →
CHOL	All	All	+0.338	.001	2	view →
PAAD	All	All	+0.195	.030	2	view →
UCEC	All	All	+0.131	.012	2	view →
PRAD	All	All	−0.063	.006	2	view →
STAD	Male	IV	−0.090	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KIAA1614-AS1–KICH

Open the KICH breakdown →