KIAA1586

Across TCGA pan-cancer cohorts, KIAA1586 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KIAA1586 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KIAA1586 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KIAA1586 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC and GBM are the cancer types where KIAA1586 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.857	.029	8	view →
GBM	DFS	Median	All	0.595	0.292	.020	5	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

KIAA1586–UCEC (OS)

Open the UCEC breakdown →