KIAA1586

Across TCGA patient cohorts, KIAA1586 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,771 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIAA1586-associated proteins across cancer lineages are ZNF451, SMAD4, and CYC1. Each is linked with KIAA1586 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA1586-to-partner and partner-to-KIAA1586 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA1586 versus ZNF451 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1586→partner) and Y-score (partner→KIAA1586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF451 →	+0.307	+0.633	<.001	<.001	3	5
PDAC	SMAD4 →	+0.285	+0.595	<.001	<.001	3	5
OV	CYC1 →	-0.576	-0.627	<.001	<.001	3	5
LSCC	DEK →	+0.277	+0.484	<.001	<.001	3	5
GBM	ENAH →	+0.358	+0.645	.004	.001	3	5
HNSC	PHF3 →	+0.192	+0.582	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,771 associations by consensus.

KIAA1586 vs ZNF451 — HNSC

Explore this scatter interactively →