KIAA1586

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1586 protein abundance is significantly associated with the RNA expression of many other genes, with 374 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1586-associated genes across cancer lineages are MEFV, AQP9, and ITFG2. Each is linked with KIAA1586 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1586-to-partner and partner-to-KIAA1586 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA1586 versus MEFV in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1586→partner) and Y-score (partner→KIAA1586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEFV →+0.829+2.035.001<.00131
UCECAQP9 →+1.582+1.895<.001.00131
UCECITFG2 →-0.437-1.426.001.00431
UCECNCOA7 →+1.075+2.142<.001<.00131
UCECSTC2 →+1.155+1.385.003.00231
UCECCCL20 →+2.227+1.834<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 374 associations by consensus.

KIAA1586 vs MEFV — UCEC

Per-sample scatter of KIAA1586 vs MEFV in UCEC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration