KIAA1549L

Across TCGA pan-cancer cohorts, KIAA1549L Mutation is linked to patient survival in 11 of 34 cancer types, making it a survival-associated KIAA1549L data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KIAA1549L Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA1549L expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

UCEC, ESCA, and DLBC are the cancer types where KIAA1549L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.834	0.620	<.001	36	view →
ESCA	OS	Median	II,III,IV	0.164	0.702	.003	33	view →
DLBC	OS	Median	II,III,IV	0.115	0.839	<.001	18	view →
HNSC	DFS	Median	All	0.437	0.699	.012	14	view →
SCLC	OS	Median	III,IV	0.164	0.653	<.001	12	view →
BLCA	OS	Median	IV	0.120	0.599	<.001	6	view →
LUSC	DFS	Median	III,IV	0.079	0.751	.024	6	view →
COAD	OS	Median	All	1.000	0.789	.021	6	view →
LUAD	OS	Median	III,IV	0.223	0.677	.006	6	view →
LGG	DFS	Median	All	0.110	0.826	<.001	3	view →
KIRP	OS	Median	All	0.248	0.705	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

KIAA1549L–UCEC (DFS)

Open the UCEC breakdown →