KIAA1549

Across TCGA pan-cancer cohorts, KIAA1549 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KIAA1549 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher KIAA1549 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA1549 expression acts as an unfavorable survival marker, although some lineages such as GBM and UCEC show a favorable association.

GBM, UCEC, and LSCC are the cancer types where KIAA1549 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.898	0.598	<.001	11	view →
UCEC	DFS	Tertile	II,III,IV	1.000	0.446	.040	4	view →
LSCC	DFS	Median	II,III,IV	1.000	0.593	.022	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KIAA1549–GBM (DFS)

Open the GBM breakdown →