KIAA1522

Across TCGA patient cohorts, KIAA1522 mutation is significantly associated with the RNA expression of many other genes, with 5,254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1522-associated genes across cancer lineages are MIR4479, RBP1, and SNORD62A. Each is linked with KIAA1522 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA1522-to-partner and partner-to-KIAA1522 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4479 grouped by KIAA1522-low versus KIAA1522-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1522→partner) and Y-score (partner→KIAA1522) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR4479 →	+0.777	+3.267	<.001	.005	3	3
COAD	RBP1 →	-1.418	-3.700	.001	.001	3	3
UCEC	SNORD62A →	+0.326	+1.578	.004	.005	3	3
UCEC	SETP14 →	+0.429	+2.513	.002	.009	3	3
UCEC	PSMB2 →	+0.460	+3.091	<.001	<.001	3	3
UCEC	YARS1 →	+0.673	+2.255	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,254 associations by consensus.

MIR4479 by KIAA1522 expression — LUAD

Explore this box plot interactively →