KIAA1210

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1210 mutation is significantly associated with the RNA expression of many other genes, with 5,667 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1210-associated genes across cancer lineages are RNF34, DEPDC1, and FAM136A. Each is linked with KIAA1210 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA1210-to-partner and partner-to-KIAA1210 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF34 grouped by KIAA1210-low versus KIAA1210-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1210→partner) and Y-score (partner→KIAA1210) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNF34 →+0.301+1.323<.001<.00135
UCECDEPDC1 →+0.490+1.280<.001<.00135
LUSCFAM136A →+0.360+1.871.003.00535
UCECUNG →+0.358+1.392.002<.00135
UCECORC1 →+0.736+1.519<.001<.00135
UCECBIRC5 →+0.639+1.302<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,667 associations by consensus.

RNF34 by KIAA1210 expression — UCEC

Box plot of RNF34 in KIAA1210-low vs KIAA1210-high samples in UCEC.

Explore this box plot interactively →

Exploration