KIAA1210

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KIAA1210 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KIAA1210 data layer compared with 10 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher KIAA1210 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA1210 expression acts as an unfavorable survival marker, although some lineages such as SCLC and KIRC show a favorable association.

SCLC, BLCA, and KIRC are the cancer types where KIAA1210 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SCLCDFSMedianAll0.6040.355.00352view →
BLCAOSTertileII,III,IV0.2830.590.00345view →
KIRCDFSMedianAll0.8630.761.00144view →
LIHCDFSQuartileII,III,IV0.2470.568.00444view →
LUADDFSMedianAll0.8390.710.00339view →
UCECDFSQuartileIV0.8760.365.01824view →
READDFSTertileAll0.4460.750.00722view →
ACCOSTertileAll0.7031.000.00218view →
PRADDFSQuartileAll0.9020.754.00818view →
OVDFSMedianIII,IV0.4060.336.01616view →
UVMOSTertileAll0.4170.822.00414view →
MESOOSQuartileII,III,IV0.5380.703.01212view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KIAA1210–SCLC (DFS)

Kaplan–Meier survival curve for KIAA1210 RNA-high vs -low samples in SCLC.

Open the SCLC breakdown →

Exploration