KIAA1210

Across TCGA patient cohorts, KIAA1210 mutation is significantly associated with the total protein of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1210-associated genes across cancer lineages are Notch1, ATM, and ASNS. Each is linked with KIAA1210 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1210-to-partner and partner-to-KIAA1210 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by KIAA1210-low versus KIAA1210-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1210→partner) and Y-score (partner→KIAA1210) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Notch1 →	+0.204	+2.005	.002	.019	3	4
UCEC	ATM →	-0.450	-2.446	<.001	<.001	3	4
UCEC	ASNS →	+0.319	+1.736	<.001	.005	3	3
UCEC	FoxM1 →	+0.192	+1.280	.004	.003	3	3
UCEC	CDK1 →	+0.083	+1.000	.036	.048	3	3
BLCA	VHL →	-0.799	-3.321	.048	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

Notch1 by KIAA1210 expression — BRCA

Explore this box plot interactively →