KIAA1210

Across TCGA cell cohorts, KIAA1210 mutation is significantly associated with the RNA expression of many other genes, with 188 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1210-associated genes across cancer lineages are CHCHD4, MAGEB5, and H4C7. Each is linked with KIAA1210 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1210-to-partner and partner-to-KIAA1210 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHCHD4 grouped by KIAA1210-low versus KIAA1210-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1210→partner) and Y-score (partner→KIAA1210) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CHCHD4 →	+0.533	+3.389	.001	.001	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	H4C7 →	+0.389	+4.643	<.001	.008	3	1
SKIN	MYL7 →	+0.339	+3.345	<.001	.007	3	1
SKIN	ARL5C →	+0.057	+3.906	.008	.002	3	1
SKIN	MAGEB10 →	+0.084	+3.510	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

CHCHD4 by KIAA1210 expression — LARGE_INTESTINE

Explore this box plot interactively →