KIAA1191

Across TCGA patient cohorts, KIAA1191 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1191-associated genes across cancer lineages are A-Raf_pS299, STAT5a, and Tuberin. Each is linked with KIAA1191 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1191-to-partner and partner-to-KIAA1191 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by KIAA1191-low versus KIAA1191-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1191→partner) and Y-score (partner→KIAA1191) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.133	-2.321	.026	.035	3	1
UCEC	STAT5a →	+0.538	+2.321	.007	.035	3	1
UCEC	Tuberin →	+0.479	+3.179	<.001	.010	3	1
UCEC	Caspase-8 →	-0.289	-2.973	.021	.035	3	1
UCEC	ERK2 →	+0.234	+2.321	.015	.035	2	1
UCEC	Claudin-7 →	-0.656	-2.321	.009	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

A-Raf_pS299 by KIAA1191 expression — UCEC

Explore this box plot interactively →