KIAA1191

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KIAA1191 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1191-associated genes across cancer lineages are ATXN3L, OR2AT4, and OR2D3. Each is linked with KIAA1191 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1191-to-partner and partner-to-KIAA1191 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATXN3L grouped by KIAA1191-low versus KIAA1191-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1191→partner) and Y-score (partner→KIAA1191) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEATXN3L →+0.014+3.297<.001.00231
LARGE_INTESTINEOR2AT4 →+0.026+3.518<.001.00131
LARGE_INTESTINEOR2D3 →+0.018+2.925.006.00731
LARGE_INTESTINEDAZ4 →+0.141+3.562.002.00231
LARGE_INTESTINEPOU5F2 →+0.028+3.115.003.00431
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ATXN3L by KIAA1191 expression — LARGE_INTESTINE

Box plot of ATXN3L in KIAA1191-low vs KIAA1191-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration