KIAA1107

Across TCGA patient cohorts, KIAA1107 mutation is significantly associated with the RNA expression of many other genes, with 2,404 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1107-associated genes across cancer lineages are OR5D3P, SNRPD3, and CENPM. Each is linked with KIAA1107 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1107-to-partner and partner-to-KIAA1107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5D3P grouped by KIAA1107-low versus KIAA1107-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1107→partner) and Y-score (partner→KIAA1107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR5D3P →	+0.036	+5.837	<.001	.001	3	2
UCEC	SNRPD3 →	+0.253	+1.760	.009	.004	3	2
UCEC	CENPM →	+0.424	+3.010	.009	<.001	3	2
UCEC	MCAT →	+0.333	+2.671	.001	<.001	3	2
UCEC	APOBEC3H →	+0.392	+1.949	.003	.008	3	2
UCEC	SAMM50 →	+0.359	+1.968	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,404 associations by consensus.

OR5D3P by KIAA1107 expression — CESC

Explore this box plot interactively →