KIAA1107

Across TCGA pan-cancer cohorts, KIAA1107 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of KIAA1107’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KIAA1107 RNA is repressed in tumor relative to normal tissue. In most cancer types KIAA1107 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, UCEC, and BRCA are the cancer types where KIAA1107 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA1107 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.884	<.001	8	view →
UCEC	All	II,III,IV	−1.039	<.001	6	view →
BRCA	Female	All	−0.526	<.001	6	view →
THCA	All	II,III,IV	−0.478	.002	6	view →
CHOL	All	All	+1.346	<.001	5	view →
LUAD	Male	All	+0.501	.005	4	view →
BLCA	Female	III,IV	+0.778	.036	3	view →
LIHC	All	All	+0.380	<.001	3	view →
LUSC	All	All	−0.241	.017	3	view →
READ	All	III,IV	−0.490	.045	2	view →
KIRC	All	All	+0.189	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

KIAA1107–KICH

Open the KICH breakdown →