KIAA1107

Across TCGA patient cohorts, KIAA1107 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1107-associated genes across cancer lineages are ATM, 4E-BP1, and 14-3-3_beta. Each is linked with KIAA1107 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1107-to-partner and partner-to-KIAA1107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by KIAA1107-low versus KIAA1107-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1107→partner) and Y-score (partner→KIAA1107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.509	-2.502	<.001	.001	3	2
UCEC	4E-BP1 →	+0.295	+2.700	.001	.005	3	2
UCEC	14-3-3_beta →	-0.092	-2.432	.007	.018	3	1
UCEC	EGFR_pY1068 →	-0.252	-1.807	.003	.004	3	1
UCEC	eIF4E →	+0.183	+2.523	.010	<.001	3	1
UCEC	A-Raf_pS299 →	-0.133	-2.321	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ATM by KIAA1107 expression — UCEC

Explore this box plot interactively →