KIAA1107

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KIAA1107 protein abundance is significantly associated with the go_rna of many other GO terms, with 656 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIAA1107-associated GO terms across cancer lineages are Diol biosynthetic process, Microtubule nucleation, and Microglia differentiation. Each is linked with KIAA1107 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1107-to-partner and partner-to-KIAA1107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Diol biosynthetic process grouped by KIAA1107-low versus KIAA1107-high in LUNG_SCLC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1107→partner) and Y-score (partner→KIAA1107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCDiol biosynthetic process →-0.153-3.922.001.00734
OESOPHAGUSMicrotubule nucleation →+0.098+1.998.007.00733
SKINMicroglia differentiation →+0.111+3.752<.001.00133
SKINNegative regulation of steroid hormone secretion →+0.068+3.751.002.00133
SKINNegative regulation of corticosteroid hormone secretion →+0.068+3.751.002.00133
SKINNegative regulation of glucocorticoid secretion →+0.064+3.752.002.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 656 associations by consensus.

Diol biosynthetic process by KIAA1107 expression — LUNG_SCLC

Box plot of Diol biosynthetic process in KIAA1107-low vs KIAA1107-high samples in LUNG_SCLC.

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Exploration