KIAA1107

Across TCGA cell cohorts, KIAA1107 mutation is significantly associated with the RNA expression of many other genes, with 876 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1107-associated genes across cancer lineages are G6PC2, TRIM42, and OR52B4. Each is linked with KIAA1107 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA1107-to-partner and partner-to-KIAA1107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, G6PC2 grouped by KIAA1107-low versus KIAA1107-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1107→partner) and Y-score (partner→KIAA1107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	G6PC2 →	+0.019	+1.777	.002	.004	3	3
UPPER_AERODIGESTIVE_TRACT	TRIM42 →	+0.029	+4.510	<.001	.003	3	3
STOMACH	OR52B4 →	+0.032	+4.285	<.001	.007	3	2
LARGE_INTESTINE	OTX1 →	+0.553	+3.169	.005	.009	3	2
LARGE_INTESTINE	RSAD1 →	+0.555	+2.265	.008	.001	3	2
LARGE_INTESTINE	CPO →	+0.103	+3.209	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 876 associations by consensus.

G6PC2 by KIAA1107 expression — LARGE_INTESTINE

Explore this box plot interactively →