KIAA0930

Across TCGA patient cohorts, KIAA0930 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0930-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and 14-3-3_beta. Each is linked with KIAA0930 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0930-to-partner and partner-to-KIAA0930 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by KIAA0930-low versus KIAA0930-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0930→partner) and Y-score (partner→KIAA0930) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.366	-2.446	.031	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+0.645	+3.459	.003	.005	3	2
UCEC	14-3-3_beta →	-0.108	-3.295	.004	.009	3	1
UCEC	eEF2 →	+0.341	+1.415	.011	.046	3	1
UCEC	EGFR_pY1068 →	-0.252	-2.169	.007	.003	3	1
UCEC	ERK2 →	+0.164	+1.807	.023	.025	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ATM by KIAA0930 expression — UCEC

Explore this box plot interactively →