KIAA0930

Across TCGA pan-cancer cohorts, KIAA0930 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated KIAA0930 data layer compared with 8 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher KIAA0930 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KIAA0930 expression acts as an unfavorable survival marker, although some lineages such as SCLC and UCEC show a favorable association.

LIHC, SCLC, and KIRC are the cancer types where KIAA0930 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.417	0.607	<.001	104	view →
SCLC	OS	Median	All	0.838	0.554	<.001	100	view →
KIRC	DFS	Quartile	II,III,IV	0.521	0.793	<.001	90	view →
MESO	OS	Median	III,IV	0.271	0.485	.002	65	view →
ACC	DFS	Median	All	0.246	0.634	<.001	64	view →
UCEC	DFS	Tertile	All	0.722	0.555	.005	34	view →
LUSC	DFS	Tertile	II,III,IV	0.707	0.463	.001	27	view →
UCS	OS	Median	IV	0.302	0.817	.002	24	view →
HNSC	OS	Tertile	All	0.581	0.819	<.001	22	view →
THCA	OS	Tertile	All	0.975	1.000	.006	20	view →
LAML	DFS	Tertile	All	0.287	0.548	.006	18	view →
STAD	DFS	Tertile	IV	0.149	0.670	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

KIAA0930–LIHC (OS)

Open the LIHC breakdown →