KIAA0930

Across TCGA cell cohorts, KIAA0930 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0930-associated genes across cancer lineages are KRTAP17-1, CWH43, and PTH2R. Each is linked with KIAA0930 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0930-to-partner and partner-to-KIAA0930 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP17-1 grouped by KIAA0930-low versus KIAA0930-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0930→partner) and Y-score (partner→KIAA0930) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	KRTAP17-1 →	+0.026	+5.369	<.001	.004	3	1
LARGE_INTESTINE	CWH43 →	+0.819	+3.491	<.001	.004	3	1
LARGE_INTESTINE	PTH2R →	+0.853	+2.716	<.001	.009	3	1
LARGE_INTESTINE	ECE2 →	+0.211	+2.791	.003	.005	3	1
LARGE_INTESTINE	GPR27 →	+1.294	+3.646	<.001	.002	3	1
LARGE_INTESTINE	TECRL →	+0.011	+3.240	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

KRTAP17-1 by KIAA0930 expression — SOFT_TISSUE

Explore this box plot interactively →