KIAA0586

Across TCGA patient cohorts, KIAA0586 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,072 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KIAA0586-associated proteins across cancer lineages are PPP4R3A, FKBP3, and AKT1. Each is linked with KIAA0586 in more than 7 cancer types. Because this analysis shows association rather than direction, both KIAA0586-to-partner and partner-to-KIAA0586 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA0586 versus PPP4R3A in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0586→partner) and Y-score (partner→KIAA0586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP4R3A →	+0.316	+0.332	<.001	<.001	3	8
LUAD	FKBP3 →	+0.336	+0.376	<.001	<.001	3	8
BRCA	AKT1 →	+0.263	+0.302	<.001	<.001	3	6
LSCC	SUPT16H →	+0.501	+0.497	<.001	<.001	3	6
GBM	MTA1 →	+0.412	+0.398	<.001	<.001	3	6
LSCC	MTHFD1 →	+0.371	+0.512	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,072 associations by consensus.

KIAA0586 vs PPP4R3A — LSCC

Explore this scatter interactively →