KIAA0513

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KIAA0513 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KIAA0513 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher KIAA0513 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA0513 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, LUAD, and HNSC are the cancer types where KIAA0513 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianAll0.5070.304<.00198view →
LUADDFSMedianIII,IV0.2300.738.00322view →
HNSCDFSQuartileAll1.0000.197.03812view →
GBMDFSTertileAll0.8030.673.0281view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KIAA0513–PDAC (DFS)

Kaplan–Meier survival curve for KIAA0513 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration