KIAA0513

Across TCGA pan-cancer cohorts, KIAA0513 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KIAA0513’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where KIAA0513 RNA is repressed in tumor relative to normal tissue. In most cancer types KIAA0513 is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

BLCA, COAD, and LIHC are the cancer types where KIAA0513 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA0513 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−2.197	<.001	11	view →
COAD	Female	II,III,IV	−1.804	<.001	11	view →
LIHC	Female	II,III,IV	+1.188	<.001	9	view →
LUAD	Female	All	−0.655	<.001	8	view →
THCA	Female	All	−0.396	<.001	8	view →
LUSC	Male	II,III,IV	−1.407	<.001	7	view →
READ	All	II,III,IV	−1.625	<.001	5	view →
KICH	Male	II,III,IV	−1.107	<.001	5	view →
BRCA	All	All	+0.362	<.001	4	view →
CHOL	All	All	+1.342	<.001	2	view →
UCEC	All	All	−0.916	<.001	2	view →
ESCA	Male	All	−1.020	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KIAA0513–BLCA

Open the BLCA breakdown →