KIAA0513

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0513 mutation is significantly associated with the RNA expression of many other genes, with 2,261 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0513-associated genes across cancer lineages are RNU6-874P, MIR6795, and MTND3P16. Each is linked with KIAA0513 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0513-to-partner and partner-to-KIAA0513 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-874P grouped by KIAA0513-low versus KIAA0513-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0513→partner) and Y-score (partner→KIAA0513) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU6-874P →+0.149+3.186<.001.00633
UCECMIR6795 →+0.131+3.812<.001.00832
BLCAMTND3P16 →+0.052+4.718<.001.00332
BLCAELL2P3 →+0.013+4.985.007.00232
UCECLAMTOR1 →+0.363+3.258.003<.00132
UCECSEC13 →+0.463+3.491<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,261 associations by consensus.

RNU6-874P by KIAA0513 expression — SKCM

Box plot of RNU6-874P in KIAA0513-low vs KIAA0513-high samples in SKCM.

Explore this box plot interactively →

Exploration