KIAA0513

Across TCGA patient cohorts, KIAA0513 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0513-associated genes across cancer lineages are eEF2, ACC1, and p38-MAPK_pT180_Y182. Each is linked with KIAA0513 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0513-to-partner and partner-to-KIAA0513 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by KIAA0513-low versus KIAA0513-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0513→partner) and Y-score (partner→KIAA0513) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.349	+1.700	.021	.044	3	2
UCEC	ACC1 →	+0.329	+3.013	.033	.018	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.438	-2.321	.021	.034	3	2
UCEC	Src_pY527 →	-0.478	-3.311	.008	.010	3	2
UCEC	ATM →	-0.676	-2.115	<.001	.017	3	2
UCEC	Bak →	+0.247	+2.584	.020	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

eEF2 by KIAA0513 expression — UCEC

Explore this box plot interactively →