KIAA0513

Across TCGA cell cohorts, KIAA0513 mutation is significantly associated with the mutation status of many other genes, with 712 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0513-associated genes across cancer lineages are FRRS1, STXBP1, and SSRP1. Each is linked with KIAA0513 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0513-to-partner and partner-to-KIAA0513 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FRRS1 grouped by KIAA0513-low versus KIAA0513-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0513→partner) and Y-score (partner→KIAA0513) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FRRS1 →	+5.772	+5.772	.002	.002	1	3
LUNG_NSCLC_LUAD	STXBP1 →	+5.772	+5.772	.002	.002	1	2
LUNG_NSCLC_LUAD	SSRP1 →	+5.772	+5.772	.002	.002	1	2
LUNG_NSCLC_LUAD	ADAM33 →	+4.772	+5.339	.004	.004	1	2
LUNG_NSCLC_LUAD	MORC3 →	+4.187	+5.000	.008	.008	1	2
LUNG_NSCLC_LUAD	MYSM1 →	+5.772	+5.772	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 712 associations by consensus.

FRRS1 by KIAA0513 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →