Across TCGA pan-cancer cohorts, KIAA0408 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KIAA0408 data layer compared with 26 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KIAA0408 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KIAA0408 expression acts as an unfavorable survival marker.

COAD, HNSC, and LGG are the cancer types where KIAA0408 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	III,IV	0.056	0.783	<.001	12	view →
HNSC	DFS	Median	IV	0.128	0.669	.011	6	view →
LGG	OS	Median	All	0.291	0.799	.004	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KIAA0408 tumor-vs-normal RNA expression · all KIAA0408 data types