Across TCGA patient cohorts, KIAA0408 mutation is significantly associated with the RNA expression of many other genes, with 5,154 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0408-associated genes across cancer lineages are GOT1, ATP5F1A, and HSPA4L. Each is linked with KIAA0408 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA0408-to-partner and partner-to-KIAA0408 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0408→partner) and Y-score (partner→KIAA0408) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GOT1 →	+0.597	+2.446	<.001	.001	3	4
UCEC	ATP5F1A →	+0.553	+3.098	<.001	<.001	3	3
UCEC	HSPA4L →	+0.790	+1.506	<.001	.002	3	3
UCEC	ZNF367 →	+0.699	+2.146	<.001	<.001	3	3
UCEC	RNASEH1 →	+0.457	+2.425	<.001	<.001	3	3
UCEC	BNIP3 →	+0.757	+1.906	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,154 associations by consensus.

Exploration

KIAA0408 survival (RNA) · tumor vs normal (RNA) · all KIAA0408 data types