KIAA0408

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0408 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0408-associated genes across cancer lineages are ERK2, GAPDH, and INPP4B. Each is linked with KIAA0408 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0408-to-partner and partner-to-KIAA0408 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0408→partner) and Y-score (partner→KIAA0408) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECERK2 →+0.206+2.736<.001<.00132
UCECGAPDH →+0.405+2.222.016.00932
UCECINPP4B →-0.231-2.087.023.00432
UCECmTOR_pS2448 →-0.129-1.980.005.00232
UCECNotch1 →+0.116+1.598.009.01932
UCECSnail →-0.204-3.906.042<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

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