Across TCGA cell cohorts, KIAA0408 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0408-associated genes across cancer lineages are HRG, PRKAG3, and CCL21. Each is linked with KIAA0408 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0408-to-partner and partner-to-KIAA0408 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0408→partner) and Y-score (partner→KIAA0408) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HRG →	+0.362	+3.855	<.001	.007	3	1
BLOOD_Leukemia	PRKAG3 →	+0.018	+3.551	.006	.009	3	1
BLOOD_Leukemia	CCL21 →	+0.134	+5.121	<.001	<.001	3	1
BLOOD_Leukemia	ZIC3 →	+0.015	+4.060	<.001	.003	3	1
BLOOD_Leukemia	KCNJ3 →	+0.446	+3.722	<.001	.009	3	1
BLOOD_Leukemia	SPATA19 →	+0.018	+4.984	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration

KIAA0408 survival (RNA) · tumor vs normal (RNA) · all KIAA0408 data types