Across TCGA cell cohorts, KIAA0408 mutation is significantly associated with the mutation status of many other genes, with 2,266 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0408-associated genes across cancer lineages are LAMA2, HCFC1, and SCN4A. Each is linked with KIAA0408 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIAA0408-to-partner and partner-to-KIAA0408 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0408→partner) and Y-score (partner→KIAA0408) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	LAMA2 →	+3.857	+4.807	.002	.002	1	5
SOFT_TISSUE	HCFC1 →	+5.502	+5.502	.003	.003	1	5
BREAST	SCN4A →	+4.857	+4.297	.009	.009	1	4
SOFT_TISSUE	PCDHA3 →	+5.502	+5.502	.003	.003	1	4
SOFT_TISSUE	TMEM132B →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	CDC42BPG →	+4.502	+5.066	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,266 associations by consensus.

Exploration

KIAA0408 survival (RNA) · tumor vs normal (RNA) · all KIAA0408 data types