KIAA0232

Across TCGA patient cohorts, KIAA0232 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0232-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and Notch1. Each is linked with KIAA0232 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA0232-to-partner and partner-to-KIAA0232 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by KIAA0232-low versus KIAA0232-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0232→partner) and Y-score (partner→KIAA0232) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ATM →	-0.442	-3.169	.015	.017	3	4
UCEC	Caspase-7-cleavedD198 →	+0.554	+2.282	<.001	<.001	3	3
BRCA	Notch1 →	+0.220	+3.006	.015	.020	2	3
SKCM	MSH6 →	-0.523	-3.321	<.001	.009	3	2
SKCM	RAD51 →	+0.364	+2.203	<.001	.031	3	2
SKCM	RBM15 →	-0.573	-3.169	.001	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

ATM by KIAA0232 expression — SKCM

Explore this box plot interactively →