KIAA0232

Across TCGA cell cohorts, KIAA0232 mutation is significantly associated with the RNA expression of many other genes, with 349 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0232-associated genes across cancer lineages are TMEM150B, FSCB, and PAPOLB. Each is linked with KIAA0232 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0232-to-partner and partner-to-KIAA0232 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM150B grouped by KIAA0232-low versus KIAA0232-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0232→partner) and Y-score (partner→KIAA0232) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TMEM150B →	+0.238	+4.058	.001	.001	3	2
LUNG_SCLC	FSCB →	+0.038	+4.209	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	PAPOLB →	+0.137	+4.510	<.001	.003	3	2
CNS	BSND →	+0.046	+4.201	<.001	.003	3	2
LARGE_INTESTINE	IGFL3 →	+0.236	+2.956	.004	.001	3	2
PANCREAS	UGT2B10 →	+0.402	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

TMEM150B by KIAA0232 expression — SOFT_TISSUE

Explore this box plot interactively →