KHSRP

Across TCGA cell cohorts, KHSRP mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KHSRP-associated genes across cancer lineages are RBMY1J, IFNA4, and DEPDC5. Each is linked with KHSRP in more than 1 cancer types. Because this analysis shows association rather than direction, both KHSRP-to-partner and partner-to-KHSRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1J grouped by KHSRP-low versus KHSRP-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHSRP→partner) and Y-score (partner→KHSRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RBMY1J →	+0.006	+4.977	<.001	.007	3	1
SKIN	IFNA4 →	+0.042	+4.977	<.001	.007	3	1
LARGE_INTESTINE	DEPDC5 →	+0.684	+3.169	<.001	.009	3	1
LARGE_INTESTINE	TOMM22 →	+0.695	+3.364	<.001	.002	3	1
LARGE_INTESTINE	JOSD1 →	+0.529	+3.364	.006	.002	3	1
LARGE_INTESTINE	EIF3D →	+0.430	+3.364	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

RBMY1J by KHSRP expression — SKIN

Explore this box plot interactively →