KHSRP

Across TCGA pan-cancer cohorts, KHSRP RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of KHSRP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KHSRP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KHSRP is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where KHSRP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KHSRP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+1.096	<.001	11	view →
COAD	All	III,IV	+0.856	<.001	11	view →
KIRC	Female	All	+0.517	<.001	11	view →
STAD	Male	II,III,IV	+1.315	<.001	10	view →
KIRP	All	III,IV	+0.786	<.001	10	view →
BLCA	All	All	+0.657	<.001	10	view →
LUSC	All	II,III,IV	+1.210	<.001	8	view →
LIHC	Female	II,III,IV	+1.150	<.001	8	view →
BRCA	All	II,III,IV	+0.392	<.001	6	view →
CHOL	Male	All	+2.021	<.001	5	view →
ESCA	All	All	+1.103	.001	2	view →
LUAD	All	II,III,IV	+0.321	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

KHSRP–HNSC

Open the HNSC breakdown →