KHK

Across TCGA patient cohorts, KHK RNA expression is significantly associated with the protein abundance of many other proteins, with 17,364 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KHK-associated proteins across cancer lineages are CAD, MSH6, and WDR1. Each is linked with KHK in more than 7 cancer types. Because this analysis shows association rather than direction, both KHK-to-partner and partner-to-KHK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KHK versus CAD in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KHK→partner) and Y-score (partner→KHK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CAD →	+0.388	+0.721	<.001	<.001	3	8
LSCC	MSH6 →	+0.670	+0.730	<.001	<.001	3	7
BRCA	WDR1 →	-0.249	-0.582	.001	.001	3	6
BRCA	CAP1 →	-0.310	-0.502	<.001	.002	3	6
LSCC	ORC4 →	+0.311	+0.587	<.001	<.001	3	6
LSCC	PARP1 →	+0.398	+0.568	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,364 associations by consensus.

KHK vs CAD — OV

Explore this scatter interactively →