KHK

Across TCGA cell cohorts, KHK RNA expression is significantly associated with the go_rna of many other GO terms, with 5,220 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KHK-associated GO terms across cancer lineages are Mitochondrial transport, Alcohol biosynthetic process, and Blood vessel morphogenesis. Each is linked with KHK in more than 12 cancer types. Because this analysis shows association rather than direction, both KHK-to-partner and partner-to-KHK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial transport grouped by KHK-low versus KHK-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHK→partner) and Y-score (partner→KHK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitochondrial transport →	+0.077	+0.887	.003	<.001	3	13
LIVER	Alcohol biosynthetic process →	+0.095	+1.775	.001	<.001	3	11
BONE	Blood vessel morphogenesis →	-0.094	-2.078	<.001	<.001	3	11
BONE	Nucleotide biosynthetic process →	+0.080	+2.116	<.001	.001	3	11
LUNG_SCLC	Regulation of epithelial to mesenchymal transition involved in endocardial cushion formation →	-0.783	-0.768	<.001	.001	3	11
LUNG_SCLC	Positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation →	-0.783	-0.768	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,220 associations by consensus.

Mitochondrial transport by KHK expression — BREAST

Explore this box plot interactively →