KERA

Across TCGA patient cohorts, KERA protein abundance is significantly associated with the RNA expression of many other genes, with 9,662 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KERA-associated genes across cancer lineages are COL1A1, NKX3-2, and LRRC17. Each is linked with KERA in more than 2 cancer types. Because this analysis shows association rather than direction, both KERA-to-partner and partner-to-KERA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KERA versus COL1A1 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KERA→partner) and Y-score (partner→KERA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL1A1 →	+1.857	+1.417	<.001	<.001	3	3
PDAC	NKX3-2 →	+1.626	+1.122	<.001	<.001	3	3
BRCA	LRRC17 →	+1.953	+1.645	<.001	<.001	3	3
PDAC	MATN3 →	+1.913	+1.003	.002	.001	3	3
PDAC	CLDN11 →	+1.291	+0.938	<.001	.001	3	3
PDAC	ITGA11 →	+1.646	+1.086	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,662 associations by consensus.

KERA vs COL1A1 — BRCA

Explore this scatter interactively →