KERA

Across TCGA cell cohorts, KERA RNA expression is significantly associated with the go_rna of many other GO terms, with 101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KERA-associated GO terms across cancer lineages are Regulation of translation at synapse, modulating synaptic transmission, Positive regulation of hair follicle maturation, and Tissue migration. Each is linked with KERA in more than 2 cancer types. Because this analysis shows association rather than direction, both KERA-to-partner and partner-to-KERA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation at synapse, modulating synaptic transmission grouped by KERA-low versus KERA-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KERA→partner) and Y-score (partner→KERA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of translation at synapse, modulating synaptic transmission →	+0.119	+0.013	<.001	.007	3	3
URINARY_TRACT	Positive regulation of hair follicle maturation →	-1.167	-0.008	<.001	.007	3	2
URINARY_TRACT	Tissue migration →	+0.075	+0.008	.005	.007	2	3
BLOOD_Leukemia	Negative regulation of calcium ion transport into cytosol →	+0.087	+0.003	.003	.004	3	2
BLOOD_Leukemia	Positive regulation of protein localization to endoplasmic reticulum →	+0.082	+0.002	.001	.007	3	2
BLOOD_Leukemia	Cholesterol biosynthetic process via lathosterol →	+0.084	+0.002	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

Regulation of translation at synapse, modulating synaptic transmission by KERA expression — BREAST

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