KDM8

Across TCGA patient cohorts, KDM8 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,392 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KDM8-associated proteins across cancer lineages are THUMPD1, ERO1A, and VEZF1. Each is linked with KDM8 in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM8-to-partner and partner-to-KDM8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM8 versus THUMPD1 in LUAD, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM8→partner) and Y-score (partner→KDM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	THUMPD1 →	+0.331	+0.332	<.001	<.001	3	6
GBM	ERO1A →	-0.423	-0.186	<.001	.005	3	5
BRCA	VEZF1 →	+0.496	+0.532	<.001	<.001	3	4
LUAD	AGO1 →	+0.219	+0.225	.009	.005	3	4
BRCA	EHBP1_S710 →	-0.540	-0.570	<.001	.005	3	4
BRCA	NOP2_S732 →	-0.869	-0.443	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,392 associations by consensus.

KDM8 vs THUMPD1 — LUAD

Explore this scatter interactively →