KDM6B

Across TCGA patient cohorts, KDM6B RNA expression is significantly associated with the protein abundance of many other proteins, with 7,614 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KDM6B-associated proteins across cancer lineages are OSBPL3_S372, S100A9_T113, and SRSF7_S233. Each is linked with KDM6B in more than 3 cancer types. Because this analysis shows association rather than direction, both KDM6B-to-partner and partner-to-KDM6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM6B versus OSBPL3_S372 in BRCA, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM6B→partner) and Y-score (partner→KDM6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OSBPL3_S372 →	-0.593	-0.540	.003	.005	3	4
GBM	S100A9_T113 →	+1.036	+0.553	.001	.002	3	3
GBM	SRSF7_S233 →	+0.848	+0.479	<.001	.002	3	3
GBM	ZDHHC7 →	-0.568	-0.652	.002	<.001	3	3
PDAC	DBR1_S514 →	+0.567	+0.654	<.001	<.001	3	3
PDAC	AKAP12_T1760 →	+0.622	+0.620	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,614 associations by consensus.

KDM6B vs OSBPL3_S372 — BRCA

Explore this scatter interactively →