KDM6B

Across TCGA cell cohorts, KDM6B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,182 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM6B-associated GO terms across cancer lineages are Response to fungicide, Viral translational termination-reinitiation, and Regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with KDM6B in more than 17 cancer types. Because this analysis shows association rather than direction, both KDM6B-to-partner and partner-to-KDM6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to fungicide grouped by KDM6B-low versus KDM6B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM6B→partner) and Y-score (partner→KDM6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to fungicide →	+0.224	+1.653	<.001	<.001	3	18
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.090	+1.162	<.001	<.001	3	15
OVARY	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.084	+1.237	<.001	<.001	3	15
LARGE_INTESTINE	Regulation of androgen receptor signaling pathway →	+0.102	+0.966	<.001	.003	3	15
BONE	Negative regulation of DNA-templated transcription initiation →	+0.166	+1.856	<.001	<.001	3	15
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.166	+1.856	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,182 associations by consensus.

Response to fungicide by KDM6B expression — STOMACH

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