KDM5D

Across TCGA patient cohorts, KDM5D mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible KDM5D-associated genes across cancer lineages are Eosinophils and GMP. Each is linked with KDM5D in more than 1 cancer types. Because this analysis shows association rather than direction, both KDM5D-to-partner and partner-to-KDM5D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by KDM5D-low versus KDM5D-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM5D→partner) and Y-score (partner→KDM5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Eosinophils →	+0.039	+3.173	.006	.049	3	1
LUSC	GMP →	+0.041	+3.264	.023	.046	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Eosinophils by KDM5D expression — LUSC

Explore this box plot interactively →