KDM5B

Across TCGA patient cohorts, KDM5B protein abundance is significantly associated with the RNA expression of many other genes, with 12,659 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM5B-associated genes across cancer lineages are RCSD1, ATP8B4, and TP53BP2. Each is linked with KDM5B in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM5B-to-partner and partner-to-KDM5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM5B versus RCSD1 in HNSC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM5B→partner) and Y-score (partner→KDM5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCSD1 →	-0.952	-0.467	<.001	<.001	3	6
HNSC	ATP8B4 →	-0.769	-0.375	<.001	<.001	3	5
HNSC	TP53BP2 →	+0.921	+0.457	<.001	<.001	3	5
HNSC	ARHGAP15 →	-0.999	-0.405	<.001	<.001	3	5
UCEC	KLHL6 →	-0.915	-0.262	<.001	.001	3	5
GBM	ACSM5 →	-0.774	-0.280	.003	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,659 associations by consensus.

KDM5B vs RCSD1 — HNSC

Explore this scatter interactively →